Thrombophlebitis may be primary or secondary. The latter form occurs in conditions known to be associated with thrombosis of veins such as childbirth, arthritis, infectious diseases, malignant tumors, recent operations, and blood dyscrasias. The primary form is of unknown cause and is often termed recurrent thrombophlebitis or thrombophlebitis migrans. The vessels affected are principally the superficial veins of the upper and lower extremities, although involvement of the visceral veins is not uncommon. Recurrent primary thrombophlebitis of the cerebral veins has been suspected clinically, but a description of the clinical as well as the gross and microscopic changes of such a case has not been recorded in the literature. For this reason the present case is of interest.
REPORT OF A CASE
The patient was a white Jewish man, 52 years, who was well until one week before admission to the hospital, when he noted fatigue and a dull frontal headache.
Smith JC. PRIMARY CEREBRAL THROMBOPHLEBITIS. JAMA. 1952;148(8):613-616. doi:10.1001/jama.1952.02930080023007