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March 15, 1952


Author Affiliations

Houston, Texas
From the Departments of Ophthalmology and Pathology, Baylor University College of Medicine.

JAMA. 1952;148(11):889-892. doi:10.1001/jama.1952.02930110011004

In 1930, Van der Hoeve1 described two cases of a scleral disease that he named scleromalacia perforans. Verhoeff and King,2 in 1938, found 14 cases in the literature, added 1 of their own, and discussed them before this section. They gave the first description (with the possible exception of a specimen reported by Holthouse in 1893 and mentioned by Smoleroff3 in his report of three cases) of an eye in this condition that had been removed and studied microscopically.

We have recently studied two cases, clinically and microscopically, that showed some features that emphasize the point that scleral disease, in the rheumatoid state, may give rise to complications that mask the original condition, so that, by the time the patient is seen by the last ophthalmologist to examine him, the origin of the disease may be obscured. Since the advent of cortisone and corticotropin, agents that promise

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