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May 17, 1952


Author Affiliations

From the Department of Pathology, Children's Hospital.

JAMA. 1952;149(3):220-227. doi:10.1001/jama.1952.02930200006002

Information concerning expanding lesions caused by localized tumefaction within the growing skull is accumulating in medical literature at an accelerating pace. Progress in diagnosis and treatment has so advanced in recent years that all practitioners must be alert to the reality that expanding lesions of the neoplastic group are by no means rare and that, although certain of these lesions may masquerade in childhood as meningoencephalitis, many reveal themselves in readily interpretable syndromes and some are favorably influenced by surgery or irradiation, or both.

This report is drawn from 104 cases studied at the Denver Children's Hospital. Only those cases in which the final clinical diagnosis was "brain tumor" are considered. A careful analysis of hospital records and surgical or autopsy material has been made. Some of the histologic diagnoses listed in the older records have been reclassified after a study of the sections in keeping with the more clearly

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