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Article
May 17, 1952

NEW ANTIHYPERTENSION DRUGS

Author Affiliations

600 S. Kingshighway St. Louis

JAMA. 1952;149(3):297. doi:10.1001/jama.1952.02930200083023

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Abstract

To the Editor:—  Recent announcements in the press of a method to control hypertension by the use of hexamethonium chloride and hydrazinophthalazine have inspired considerable confusion and conflicting comments in both lay and medical circles. Some tabloid newspapers gave a distorted, overenthusiastic view, other papers were reasonably factual, but several reprinted follow-up stories inspired by another investigator branding the method as "dangerous." In addition, literature mailed to physicians by the manufacturer of a preparation of hexamethonium chloride contained erroneous statements attributed to me. Since the truth lies between these conflicting statements, I am attempting to clarify the confusion.A method for the partial temporary control of arterial hypertension has been developed, a preliminary report of which was published in the A. M. A. Archives of Internal Medicine (89:523 [April] 1952). This method has been extended to include approximately 120 patients suffering from arterial hypertension of all degrees of severity,

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