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February 28, 1953


Author Affiliations

Milwaukee; Nashville, Tenn.

JAMA. 1953;151(9):738-739. doi:10.1001/jama.1953.02940090040007g

Cullingworth in 1879 published an account of a patient, who had pelvic masses, ascites, and hydrothorax. By 1932 five more cases were added and Meigs and Cass in their report in 1937 brought this syndrome to the attention of the medical world. The syndrome is now called Meigs' syndrome. A review of the literature in 1951 revealed that less than 100 cases have been reported.

This condition usually occurs in women past the menopause. The symptoms have chiefly been dyspnea and swelling of the abdomen, although weakness, chest and abdominal pain, and cough have been present. The duration of the symptoms may run from days to several years. The location of the pelvic mass has been, equally divided between the two sides and in about 10% of the cases has been bilateral. The usual site of the pleural effusion has been on the right side. In 10% of the cases

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