Although mumps is a self-limited and usually a benign disease, it can cause a prostrating illness in the man past puberty. The complications of orchitis, meningo-encephalitis, and pancreatitis occur in 30 to 50% of adult men with epidemic parotitis. Therefore, any therapeutic agent that shows promise of permitting the patient to return to full activity at an earlier date is worth evaluating.
There have been several reports suggesting that aureomycin may be effective in treating mumps. Langley and Bryfogle reported three patients with uncomplicated mumps in whom they felt that aureomycin significantly shortened the period of morbidity.1 Schmuttermeier and associates reported one patient with orchitis,2 and Spinelli and co-workers reported four patients with orchitis in whom aureomycin seemed to shorten the febrile course and period of incapacity.3 Schaub reported a series of 17 patients treated with aureomycin whom he compared with a similar group treated symptomatically in
Homer L, Donovan WN. AUREOMYCIN IN MUMPS. JAMA. 1952;150(5):465-467. doi:10.1001/jama.1952.03680050031009