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Article
June 9, 1956

REVERSIBLE UREMIC STATES

Author Affiliations

New Haven, Conn.

From Yale University School of Medicine.

JAMA. 1956;161(6):494-499. doi:10.1001/jama.1956.02970060008003
Abstract

• Renal circulation is sometimes temporarily impaired by cardiac failure; the resultant renal insufficiency is then amenable to treatment of the failing heart. This was seen in a patient in whom digitalization produced a gratifying diuresis, a fall in the nonprotein nitrogen of the blood, and marked symptomatic improvement.

Renal disease may be either caused or complicated by obstructions lower down in the urinary tract. This is illustrated by a case of anuria with uremia and mild hypertension in which recovery followed the relief of bilateral ureteral strictures.

Hypercalcemia proved to be the cause of albuminuria and uremia in a patient who had been receiving a daily total of 12 gm. of calcium in various forms as treatment for duodenal ulcer. On a diet relatively low in calcium his renal function was restored to normal.

Other treatable causes of renal impairment include dehydration, infection, salt depletion, alkalosis, and loss of potassium. In addition, there are self-limited, reversible types of renal failure. For these reasons the prognosis in uremia is not necessarily hopeless.

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