• Many allergic patients fail to respond to the usual type of allergy management, and in most of these cases there is a large psychogenic component that must be treated before clinical improvement can be expected. Tranquilizing drugs provide available therapy to block certain interneuronal pathways adversely affected by anxiety and tension. The treatment of allergies can yield better results and longer-lasting successes by utilizing the "total" or combined type of treatment that embraces both the physical and the emotional factors involved. However, the tranquilizers should be used only as an adjunct to the therapy of allergy where there are certain states of anxiety and tension, and not as a replacement of accepted diagnostic and curative procedures.
Eisenberg BC. ROLE OF TRANQUILIZING DRUGS IN ALLERGY. JAMA. 1957;163(11):934-937. doi:10.1001/jama.1957.02970460024007