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March 16, 1957

Chemosurgery in Cancer, Gangrene and Infections: Featuring a New Method for the Microscopically Controlled Excision of Cancer

JAMA. 1957;163(11):994. doi:10.1001/jama.1957.02970460084024

To those interested in the treatment of neoplastic diseases, the work of the author in the chemosurgery of cancer over a period of many years is well known. In this handsome and profusely illustrated book the author describes the methods by which he has brought the ancient art of the treatment of surface neoplasms by means of caustic preparations to a scientific precision. In his hands, and probably in the experience of some of his pupils, the chemosurgical technique is an effective means of treatment for certain lesions, but it is a highly specialized procedure not only requiring elaborate physical resources but also imposing on the therapist the necessity of being his own microscopist. The painstaking and elaborate fixation of tissue in successive planes and the repeated removal of tissue after fixation in situ for careful microscopic examination makes the technique unnecessarily time-consuming to the professional personnel involved and much

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