• Cutaneous lesions in the axilla were observed in one man aged 52 years and three women aged 41, 28, and 17 years. The lesions were papular or nodular in gross appearance; on microscopic examination of biopsy specimens obtained from three of the patients the lesions were found to have a granulomatous structure containing epithelioid and giant cells and infiltrated with lymphocytes. In each case the patient had been using a deodorant stick containing sodium zirconium lactate. Therapy with solid carbon dioxide was moderately effective.
Sheard C, Cormia FE, Atkinson SC, Worthington EL. GRANULOMATOUS REACTIONS TO DEODORANT STICKS. JAMA. 1957;164(10):1085-1087. doi:10.1001/jama.1957.02980100041008