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Article
July 20, 1957

RELIEF OF JUVENILE INVOLUNTARY MOVEMENT DISORDERS BY CHEMOPALLIDECTOMY

Author Affiliations

New York

Director, Department of Neurologic Surgery, St. Barnabas Hospital, and Professor of Clinical Neurosurgery, New York University-Bellevue Medical Center.

JAMA. 1957;164(12):1297-1301. doi:10.1001/jama.1957.02980120001001
Abstract

• Chemopallidectomy is a neurosurgical procedure involving the injection of small amounts of absolute alcohol (or a special alcohol solution) into the globus pallidus. The technique has relieved the tremor and rigidity of Parkinsonism, and has also relieved dystonic movements and fixed postures, choreoathetosis, and hemiballismus. In the reported series, 20 of 30 patients undergoing this operation were relieved of their involuntary movements. Chemopallidectomy is aimed only at the relief of hyperkinetic or involuntary movement disorders, and it will not relieve other abnormalities that are so frequently noted in congenital brain lesions.

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