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January 25, 1958


Author Affiliations

Vice-president and Medical Director Warner-Chilcott Laboratories Morris Plains, N. J.

JAMA. 1958;166(4):401. doi:10.1001/jama.1958.02990040087020

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To the Editor:—  In his article on hypothyroidism (J. A. M. A.165:121 [Sept. 14] 1957), Dr. Arnold Jackson stated "... the thyroid tablets lost their potency if they were more than three months old." His reference was to desiccated thyroid tablets; however, as many physicians have assumed that the statement applied to all forms of thyroid derived from glandular sources, including thyroglobulin, we should like to take issue with this statement at least so far as it applies to our product.Although we repeatedly assay our thyroglobulin to assure ourselves of its biological potency, nevertheless, after publication of Dr. Jackson's article, we retested by basal metabolic rate two-year-old and seven-year-old reference samples of Proloid stored at room temperature, and also rechecked previous assays which included the goiter prevention tests in rats. The results are presented in the table.Standard 06985 replaced standard 5640 after supplies of the latter were

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