In 28 out of 1,331 gallbladders removed surgically, grossly polypoid lesions were found on the vesical mucosa. These growths are small and soft; they are easily torn from their pedicles and especially difficult to recognize if gallstones are associated with them. They occur in several varieties such as the inflammatory polyp, the cholesterol polyp, the adenoma, the adenomyoma, and the polyp harboring a carcinoma. It is sometimes, but not always, possible to distinguish them from radiolucent gallstones in roentgenograms of good quality. Since there is reason to suppose them potentially malignant, the authors believe it wise to consider cholecystectomy unless there are definite contraindications.
Carrera GM, Ochsner SF. POLYPOID MUCOSAL LESIONS OF GALLBLADDER. JAMA. 1958;166(8):888-892. doi:10.1001/jama.1958.02990080032007