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Article
December 12, 1959

CHEMICAL EVIDENCE OF INCIDENCE OF HYPOTHYROIDISMSTUDY OF EMPLOYED MEN AND WOMEN, PHYSICIANS, AND PROFESSIONAL BLOOD DONORS

Author Affiliations

Los Angeles

From the School of Medicine, University of Southern California, and the Los Angeles County General Hospital.

JAMA. 1959;171(15):2045-2048. doi:10.1001/jama.1959.03010330007003
Abstract

Determinations of protein-bound iodine levels were carried out on serums obtained from 1,823 men in industry, 2,182 male commercial blood donors, 735 male physicians, and 1,015 women employees of a general hospital. The mean for the first group of men was 5.33 mcg. % with a standard deviation of ±1.19; the mean for the women was 5.67 mcg.% with a standard deviation of ±1.22. On the basis of interviews, physical examinations, and laboratory studies on smaller groups of subjects it was concluded that protein-bound iodine values below 4 mcg.% in men or 4.5 mcg.% in women are diagnostic of hypothyroidism. In these four populations, such evidence of hypothyroidism was found in 4.94%, 9.2%, and 4.2% among the men and 7.3% among the women.

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