[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
January 16, 1960


Author Affiliations

125 E. 72nd St. New York 21.

JAMA. 1960;172(3):265-266. doi:10.1001/jama.1960.03020030059018

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  We read with interest the excellent paper, "Master Two-Step Exercise Test in Clinically Unselected Patients," by Dr. A. J. Brody, in The Journal, Oct. 31, page 1195. Brody's major conclusions deserve comment and, perhaps, amplification. It is gratifying that the value of a negative double two-step test result has again been demonstrated. In our experience, and that of other investigators, notably Robb and others (Tr. A. Life Insurance M. Dir. America40:52,1956) and Mattingly and others (Research Report 75-57, Walter Reed Army Institute of Research [May] 1957), a negative Master test practically, although not infallibly, excludes a diagnosis of myocardial ischemia at the time of testing. Brody's finding, that only 4.2% of his negative reactors subsequently developed coronary disease, closely parallels our own reports (Master: Proceedings of the Third World Congress of Cardiology, Brussels, 1958, p. 138; Master and others: Advances in Cardiology, New York, 1959,

First Page Preview View Large
First page PDF preview
First page PDF preview