An attempt was made to detect possible relationships between abnormalities in the placenta and subsequent aberrant growth in the infant. In a series of 654 deliveries, 262 placentas (40%) showed infarcts, fibrinoid degeneration, areas of old or recent abruption, and other malformations or variations. The corresponding 262 infants were compared with the 392 infants born with normal placentas. The differences showed that abnormality of the placenta increases the probability of nutritional disturbances in the first six months of postnatal life. Gross examination of the placenta can forewarn the physician of some common problems in the immediate postnatal period.
Hepner R, Bowen M. THE PLACENTA AND THE FETUS. JAMA. 1960;172(5):427-432. doi:10.1001/jama.1960.03020050019006