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To the Editor:—
The article "Reactions to Poliomyelitis Vaccine" by Christensen in The Journal, Oct. 17, 1959, page 869, implies certain things about reactions to the penicillin contained in poliomyelitis vaccine which are not necessarily true. The statements that, "It seems likely that most of the severe reactions would have been reported," and that Eli Lilly & Co. has had only 284 complaints after 184 million ml. of the vaccine was distributed are illogical. Even if all reactions known were reported to the company, as noted by the A. M. A. Council on Drugs in discussing the similar problem of trace amounts of penicillin in milk (J. A. M. A.171:49 [Sept. 5] 1959), such penicillin reactions "have gone unreported and unrecognized." I had a paper on penicillin reactions to poliomyelitis vaccine in The Journal, Aug. 9, 1958, page 1807, but I did not report to the company, although
Zimmerman MC. REACTIONS TO POLIOMYELITIS VACCINE. JAMA. 1960;172(10):1084. doi:10.1001/jama.1960.03020100092024