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April 2, 1960


Author Affiliations

561 N. 15th St. Milwaukee 3.

JAMA. 1960;172(14):1556-1557. doi:10.1001/jama.1960.03020140092022

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To the Editor:—  After reading the editorial, "Bleeding and Clotting Times," in The Journal, Jan. 2, page 63, I am prompted to follow Al Smith's slogan: "Let's take a look at the record." Is it true that "the ensuing 40 years of research brought not a clarification of the subject (theories of coagulation)...?"Thirty years ago, when I was an intern at Blockley, Dr. Eldridge Eliason was called in consultation to see one of my patients who had extreme jaundice. He remarked: "If I don't operate she will die, and if I do operate she will probably die from postoperative bleeding." That was the era when blood clotting theories were simple, and only a few terms like antithrombin and antiprothrombin confused the medical student. After Drs. Bancroft, Stanley-Brown, and I (Am. J. M. Sc.190:501 [Oct.] 1935) showed, by a simple method, the one-stage prothrombin time, that the prothrombin

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