Twenty college students, 19 men and 1 woman, subsisted for three to five days on a liquid diet containing 300 Gm. of carbohydrate, 100 Gm. of vegetable fat, and no protein. The unique feature of the diet was its almost complete avoidance of electrolytes; the elements ingested daily amounted to 45 mg. of sodium, 32 mg. of potassium, 2.7 mg. of calcium, 64 mg. of chloride, and 84 mg. of phosphorus. Daily 24-hour urine specimens were obtained from the students for two days of unrestricted diet and during the study period. Serum electrolyte and nonprotein nitrogen measurements were made during the prediet period and at the end of the diet period. The diet produced a prompt decrease in urinary electrolyte excretion. It was palatable and well tolerated. It promises to be useful in the diagnosis as well as in the treatment of various conditions in which electrolyte control is important.
Vertes V. ELECTROLYTE-FREE LIQUID FORMULA DIETMETABOLIC EFFECTS AND POSSIBLE CLINICAL USES. JAMA. 1960;172(17):1893–1897. doi:10.1001/jama.1960.03020170019005