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May 14, 1960


Author Affiliations

J #554 entre 25 y 27 Vedado Habana, Cuba.

JAMA. 1960;173(2):202. doi:10.1001/jama.1960.03020200074022

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To the Editor:—  Your abstract of Motta Maia's paper (J. A. M. A. 172:384 [Jan. 23] 1960) is most timely since it sheds light on an old but seldom used method, the treatment of postoperative ileus with drugs. Results obtained in the past with several peristalsis stimulating drugs, such as hypertonic saline solution, vasopressin, and neostigmine, were so poor that the procedure was claimed to be of dubious value. Now Motta Maia brings back the same old recipe with a new powerful ingredient, ambenonium chloride; 1 cc., containing only 62.5 mcg. of the drug, produces a better response than a full milligram of the old neostigmine preparation.Prophylaxis or treatment of postoperative adynamic ileus or urinary retention are so easily obtained with ambenonium chloride that after trying it one wonders if intubation is ever needed in the treatment of such conditions.Our work, which followed the same lines as

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