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Article
June 11, 1960

SIMPLE METHOD FOR THE MEASUREMENT OF ALVEOLAR CARBON DIOXIDE

Author Affiliations

Boston

From the Department of Medicine of the Harvard Medical School, the Medical Research Department of the Yamins Research Laboratories, and the Medical Service, Beth Israel Hospital.

JAMA. 1960;173(6):671-674. doi:10.1001/jama.1960.73020240011010e
Abstract

Measurement of alveolar carbon dioxide tension is important in the diagnosis and care of patients with pulmonary disease, during anesthesia, in coma, and in other conditions with increased or depressed alveolar ventilation. A previous communication1 described a simple, accurate, inexpensive apparatus for the bedside measurement of alveolar carbon dioxide tension. The present report deals with the clinical application of this method to eucapnic, hypercapnic, and hypocapnic subjects. The results are compared with simultaneous measurement of arterial blood carbon dioxide tension, and a method is outlined for use of the apparatus in patients in coma or unable to produce an adequate alveolar sample on a single breath.

Materials and Methods  Nineteen patients referred for pulmonary function studies and presenting a variety of cardiopulmonary diseases were studied. Simultaneous measurements were made of the carbon dioxide tension of their arterial blood and end-expired or rebreathing gas samples, or both.The principle of

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