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June 18, 1960

Electrophoresis in Physiology

JAMA. 1960;173(7):852. doi:10.1001/jama.1960.03020250108032

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Electrophoresis, the migration of particles under the influence of an electric field, is discussed in the light of its application to biology. A chapter on immunoelectrophoresis, the study of immunity by enumeration and identification of protein components in a mixture with electrophoresis was written by M. D. Poulik, of the Child Research Center of Michigan, Detroit. Particular emphasis is placed on the value of electrophoresis in physiology and medicine. In the discussion of medicine, for example, attention is called to the use of electrophoresis on protein pathological conditions in plasma and in other bodily fluids and to the important finding that the hemoglobin level of patients with sickle cell anemia has an electrophoretic mobility different from that of normal adult hemoglobin levels. One chapter is devoted to the research and studies of the author and associates. Electrophoresis is a specialized field, and the author has brought the subject up to

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