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To the Editor:—
I would like to comment on the article, "Cholecystography with Bunamiodyl," by Meszaros and Rich in The Journal, April 23, page 1884. I have been using bunamiodyl (Orabilex) in this hospital for the last six months. The prescribed dosage has been adhered to, and the examinations are often combined with those of the upper gastrointestinal tract. In 111 examinations made with bunamiodye only one patient has had diarrhea, one has had dysuria, and five patients have had a moderate urticaria over the extremities and neck.Bunamiodyl was used as a medium for gallbladder examinations of executives of a large company, and after 43 examinations I had to discontinue its use. There were five reactions: two patients had a severe esophageal spasm; one patient had a severe urticaria over the extremities and entire trunk; and two patients had a moderately severe urticaria over the extremities. These five patients
Tatum CF. REACTION TO BUNAMIODYL. JAMA. 1960;173(13):1507-1508. doi:10.1001/jama.1960.03020310095032