[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.158.173.184. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
September 3, 1960

PREANESTHETIC MEDICATION

Author Affiliations

The University of Michigan Ann Arbor, Mich.

JAMA. 1960;174(1):92-93. doi:10.1001/jama.1960.03030010094030

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  The article by Dr. Wallace in The Journal, June 18, page 797, is timely, since the techniques of preanesthetic medication generally are undergoing reevaluation. I am concerned that there may some misunderstanding in the use of the word "sympathomimetic" for scopolamine or atropine in the subtitle and text.Scopolamine and atropine, both centrally and peripherally, block some of the actions of acetylcholine, the neurohumoral agent released by cholinergic neurons, many of which are involved in the parasympathetic nervous system. Therefore, these drugs should be called parasympathetic-blocking or cholinergic-blocking agents. Sympathomimetic drugs mimic the action of catechol amines such as epinephrine or arterenol (Norepinephrine). Thus the casual reader may misunderstand the form of the premedication (promethazine and scopolamine) used by Dr. Wallace.

First Page Preview View Large
First page PDF preview
First page PDF preview
×