[Skip to Content]
[Skip to Content Landing]
Article
October 15, 1960

THIAZIDE DIURETICS IN TOXEMIA OF PREGNANCY

Author Affiliations

Los Angeles.

JAMA. 1960;174(7):887-888. doi:10.1001/jama.1960.03030070065018

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

In the June 11 issue of the British Medical Journal, page 1807, appeared a report by Drs. John Watt and Elliot E. Philipp of five cases of intrauterine fetal death which occurred in patients with toxemia of pregnancy who were taking chlorothiazide. These authors implied in their communication that these fetal deaths were related to the use of the oral diuretics.

In his comments regarding the above communication, published in the July 9 issue of the same journal on page 148, Dr. R. T. Sears stated that, while diuretics remove some of the manifestations of the disease, they do not attack directly its cause. He further stated that the intrauterine deaths may have been caused by the placental changes which occur in toxemia and may have had no relation to the use of diuretics. Because of the many inquiries which have been made regarding these controversial communications, it seems desirable

First Page Preview View Large
First page PDF preview
First page PDF preview
×