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The introduction of metal-binding or chelating agents has resulted in unique and fascinating observations on trace metals and their role in normal and abnormal physiology. In the past few years, data have been accumulating at a rapid rate, and, in order to present as complete a summation of our present knowledge of this subject as possible, a conference of outstanding workers and contributors in this field was held. This book represents a crystallization of the material presented, with a comprehensive survey of activities, both those accomplished and those in progress.
The papers are organized to cover six facets of the problem, ranging from fundamental concepts in trace metal research through clinical application of metal-binding agents, with discussion of practical as well as hypothetical applications of the metalbinding principle in clinical therapy. At the close of each group of papers, an informal panel discussion is recorded with questions posed and answered
Bigg E. Metal-Binding in Medicine: Proceedings of a Symposium Sponsored by Hahnemann Medical College and Hospital, Philadelphia. JAMA. 1960;174(13):1758. doi:10.1001/jama.1960.03030130086038