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December 17, 1960

Photosensitizing Therapeutic Agents

Author Affiliations

Miami, Fla.

JAMA. 1960;174(16):2043-2048. doi:10.1001/jama.1960.03030160029007

The antibacterial sulfonamides, the related group of hypoglycemic agents, the group of chlorothiazide diuretics, and the phenothiazine group of central sympathetic suppressants may induce cutaneous reactions when the patient is exposed to sunlight. There are numerous reports that demethylated chlortetracycline may act as a photosensitizing agent, and a few reports that griseofulvin may do so. Photosensitization dermatoses are infrequently associated with serious reactions.