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January 7, 1961

Ruptured Peptic Ulcer

Author Affiliations

435 N. Roxbury Dr. Beverly Hills, Calif.

JAMA. 1961;175(1):67. doi:10.1001/jama.1961.03040010069024

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To the Editor:—  In the paper, "Ruptured Peptic Ulcer During Triamcinolone Therapy," in The Journal June 25, page 900, the authors neglected to mention that ACTH can be an extremely important cause of ruptured peptic ulcer, especially while the patient is receiving large amounts of aspirin. Because of this, the title of the case report seems to be a misnomer. Acute perforations are not uncommon following such a combination of therapy, and frequent use of non-absorbable antacids should be the rule.

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