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To the Editor:—
Even though pediatrics remains largely an art, it is becoming increasingly a science. The physical sign is objective and verifiable evidence of pathologic change. It has indisputable value as a unit of solid evidence in laying the foundation for accurate diagnosis, regardless of the confusing data derived from the history or the inconsistencies of statements voiced by the parents. The optimal physical sign is a direct function of its diagnostic delimitation in a given field, revealed to an alert observer who is prepared by other features of the history or examination to search for it.Dr. Myers' paper, "The 'Nasal Crease,' a Physical Sign of Allergic Rhinitis," published in The Journal, Oct. 29, 1960, page 1204, contains a special example of a general sign of constitutional allergy described by me in the Archives of Dermatology and Syphilology (36:342 [Aug.] 1937). This early sign of later allergy
Kugelmass IN. The Physical Sign in Pediatrics. JAMA. 1961;175(9):822. doi:10.1001/jama.1961.03040090082024