The treatment of tinea versicolor in the past has been unsatisfactory. Recurrences were frequent despite prolonged daily applications of the medications available. A new compound, 9-aminoacridinium 4-hexylresorcinolate, in 3 topical vehicles (cream, lotion, and aerosol spray), has been evaluated by clinical and laboratory criteria in a series of 40 patients with this mycotic infection. Good to excellent results were obtained in 39 patients. In 32 of these, complete clearing occurred after a single course of 4 to 8 weeks; in 7 others it occurred after a second similar course. Only one patient had poor results, with prompt recurrences after repeated courses. No signs of primary irritation or allergic sensitization were observed in any case, and acceptance by patients was excellent.
Zimmerman EH. New Therapeutic Agent for Tinea Versicolor9-Aminoacridinium 4-Hexylresorcinolate. JAMA. 1961;176(1):23–25. doi:10.1001/jama.1961.03040140025007