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May 13, 1961

Gastroesophageal Regurgitation

Author Affiliations

Los Angeles

From the Gastroenterology Section, Wadsworth Hospital, Veterans Administration Center, and the departments of Medicine and Physiology, University of California.; Dr. Bettarello is a Kellogg Foundation Fellow.

JAMA. 1961;176(6):498-500. doi:10.1001/jama.1961.03040190020006
Abstract

The esophagus was studied clinically to elucidate the subjective experience called heartburn. Apparatus was developed for recording acidity within the esophagus simultaneously with intraesophageal and intragastric pressure and with signals representing the patient's sensations. The evidence showed that heartburn is distinct from the sensation that accompanies distension of the esophagus. Heartburn occurred when acidity was high in the esophagus; and it disappeared when the acidity decreased.

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