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May 13, 1961

QUALITY AND CONTROLS IN THE BACTERIOPHAGE TYPING OF STAPHYLOCOCCI

JAMA. 1961;176(6):521. doi:10.1001/jama.1961.03040190043013
Abstract

The problem of hospital-acquired, antibiotic-resistant staphylococcal infections has greatly increased the interest of physicians in the available means for recognizing the source of these infections as a step toward their elimination. Although Cowan1,2 and more recently Oeding3,4 have developed serologic methods for grouping and typing different strains of staphylococci, the general lack of uniform reagents has limited the use of serologic typing as a method for epidemiologic study. Greater experience has been gained in bacteriophage typing.5-7 In this method the lysogenicity of different strains of staphylococci with a collection of standard bacteriophages permits certain conclusions regarding the similarities or differences of the strains tested. In the control of staphylococcal infections it is important to know whether most of the victims are infected with a strain of common origin or whether the cases are occurring from infection with multiple strains of diverse origin. Contrary to some popular belief,

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