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May 13, 1961

Christmas Disease-Reply

Author Affiliations

2695 Center St., Pittsburgh 5.

JAMA. 1961;176(6):552. doi:10.1001/jama.1961.03040190074030

To the Editor:—  In reply to Dr. Lamar, concerning my use of the eponym Christmas disease instead of hemophilia B, I might state that I could have also used the terms PTC deficiency or Factor IX deficiency and by so doing confused or at least discouraged the average reader.I would like to defend my use of the eponym Christmas disease. In the bibliography to my paper in Hemophilia and Other Hemorrhagic States, edited by Brinkhous and DeNicola, the eponym Christmas disease is mentioned at least 20 times. In the introduction to this book, there is a glossary of synonyms and symbols containing 72 definitions. I quote 2 of these: "Christmas disease, a hemophilioid disease; prototype a patient named Christmas, Factor IX deficiency." "Hemophilia B, PTC deficiency, Christmas Disease." These are the only definitions of hemophilia B in the glossary. In addition, in the index of this book under

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