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July 8, 1961

Neurogenic Tumors Simulating Infectious ProcessReport of Two Cases of Diagnostic Interest

Author Affiliations

Lynchburg, Va.

From the Department of Neurological Surgery, Medical College of Virginia.

JAMA. 1961;177(1):65-68. doi:10.1001/jama.1961.73040270047013a

NEOPLASTIC lesions occasionally may simulate inflammatory entities and, treated as such, remain unrecognized until a late stage, if ever. This could be explained by an increased cellular activity and metabolism reactional to a pathological stimulus, still very much unknown in nature in tumors. Thus, "rubor, calor, tumor, and dolor," characteristics of inflammation, are not uncommonly found in neoplasms. A certain clinical resemblance, the rarity of the involved pathology, and the treatment used in 1 of them leads us to present the following 2 cases.

Report of Cases 

Case 1.—  A 13-year-old Negro boy was admitted in January, 1959, to St. Philip Hospital, Medical College of Virginia Hospitals, with a diagnosis of mastoiditis. In September of 1958, he developed a painful stiffness of the neck; he was treated first with a muscle relaxant, methocarbamol (Robaxin), and later with antibiotics, as an abscess had been suspected over the left mastoid region.

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