NEOPLASTIC lesions occasionally may simulate inflammatory entities and, treated as such, remain unrecognized until a late stage, if ever. This could be explained by an increased cellular activity and metabolism reactional to a pathological stimulus, still very much unknown in nature in tumors. Thus, "rubor, calor, tumor, and dolor," characteristics of inflammation, are not uncommonly found in neoplasms. A certain clinical resemblance, the rarity of the involved pathology, and the treatment used in 1 of them leads us to present the following 2 cases.
Report of Cases
A 13-year-old Negro boy was admitted in January, 1959, to St. Philip Hospital, Medical College of Virginia Hospitals, with a diagnosis of mastoiditis. In September of 1958, he developed a painful stiffness of the neck; he was treated first with a muscle relaxant, methocarbamol (Robaxin), and later with antibiotics, as an abscess had been suspected over the left mastoid region.
Botton JE. Neurogenic Tumors Simulating Infectious ProcessReport of Two Cases of Diagnostic Interest. JAMA. 1961;177(1):65–68. doi:10.1001/jama.1961.73040270047013a