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July 29, 1961

Studies on MelanomaThe Effect of Pregnancy on Survival in Human Melanoma

Author Affiliations

Boston; Berkeley, Calif.

From the Children's Cancer Research Foundation and the Department of Pathology, The Children's Hospital Medical Center (Dr. White); and from the California Tumor Registry, Bureau of Chronic Diseases, Department of Public Health. State of California (Mr. Linden, Dr. Breslow, and Miss Harzfeld).

JAMA. 1961;177(4):235-238. doi:10.1001/jama.1961.03040300007002

Pregnancy data have been analyzed in 71 women between the ages of 15 and 39 years, all of whom had proved melanoma. All pregnancies occurring within 1 year before diagnosis and 5 years after diagnosis were noted, and survival of these women was plotted. Thirty patients were pregnant within the 6-year period defined; 31 were not pregnant during this period, and for 10, no history of pregnancy could be obtained. Five-year survival was slightly higher in the pregnant group than in the nonpregnant. Comparing 5-year survival in pregnant and nonpregnant women, with age and stage of disease taken into account, survival was equal in the 2 groups. No deleterious effect of pregnancy on survival of a group of women with melanoma was demonstrated.