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August 5, 1961


JAMA. 1961;177(5):326. doi:10.1001/jama.1961.03040310044010

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Insidious venous thrombosis remains one of the most serious and least understood vascular diseases, causing disabling symptoms and occasionally death from pulmonary embolism. Statistical review of clinical experience with thromboembolism since the turn of the century reveals no significant trend in incidence of the disease. Moreover, the incidence of pulmonary embolism resulting from insidious venous thrombosis has remained relatively constant, although anticoagulants and other therapeutic measures have been widely used clinically for control of this complication. Thus, any method of definitive treatment of either the primary thrombosis or the secondary embolic phenomena would be welcomed by the profession.

In general, treatment of deep venous thrombosis of the calf and thigh consists of supportive measures, often in conjunction with anticoagulants. If pulmonary embolism does not ensue, the results of treatment are considered successful. Although popular more than 5 years ago, surgical ligation of the superficial femoral veins for prevention of pulmonary

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