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August 5, 1961

Carcinoma in Situ of the Uterine Cervix

JAMA. 1961;177(5):352. doi:10.1001/jama.1961.03040310070028

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With the growing use of cervical smears to detect the presence of abnormal cells desquamated from the cervix, the problems of the pathologist and clinician in diagnosing early cervical carcinoma have considerably increased. Any experienced pathologist can make a histological diagnosis on a clear-cut case with ease, but when less distinctive changes are present, it is often difficult to determine the potentialities for epithelial growth. This includes the differentiation of carcinoma in situ from abnormalities which are benign and reversible on the one hand, and from early invasive carcinoma on the other.

In this book, the authors contribute a great deal to the diagnosis of carcinoma in situ of the cervix. They demonstrate different histologic patterns in excellent photomicrographs which will be of help to any pathologist examining histologic sections of the cervix. They stress the fact that there are all gradations between a benign and malignant state, and show

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