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October 7, 1961

Systemic Lupus Erythematosus

JAMA. 1961;178(1):94. doi:10.1001/jama.1961.03040400096043

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Abstract

The author declares that systemic lupus erythematosus should be considered one of the "great imitators," along with syphilis, tuberculosis, or malaria. The variable course and the widely diverse manifestations can cause difficulty in achieving a correct diagnosis. With this in mind Dr. Larson discusses the disease in systematic fashion, drawing chiefly on a series of 200 cases clinically so diagnosed at the Presbyterian Hospital in New York, over the past 20 years. He takes up, by organs, the various clinical manifestations which the disease may display, and offers brief illustrative case histories. The orientation is essentially clinical, and there is only scant mention of anatomical findings. However, there is a good discussion of the laboratory features of the disease, especially of the LE cell factor. There is a bibliography of 229 titles. The book, attractively published, is in no sense a definitive analysis of our knowledge on this disease, but

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