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To the Editor:—
In The Journal of July 29 (177: 281, 1961), Dr. Harry Horwich, in answer to a question concerning arcus senilis, states that the presence of arcus is not medically significant.Recent lipid metabolic studies performed by Dr. John Finley and myself on a group of young patients with arcus revealed marked abnormalities in the majority as evidenced by hypertriglyceridemia, hyperchylomicronemia, and impaired radioactive fat tolerance. These findings were reported at the recent meeting of the AMA and appeared in the August issue of Archives of Ophthalmology.Accordingly, it is our opinion that arcus senilis, especially when present in the younger subject, is evidence of the presence of abnormal fat metabolism and is definitely medically significant.
Berkowitz D. Arcus Senilis. JAMA. 1961;178(3):355. doi:10.1001/jama.1961.03040420095036