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October 21, 1961

Functional Behavior of the Microcirculation

JAMA. 1961;178(3):356. doi:10.1001/jama.1961.03040420096040

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The aim of this book is to describe microcirculatory activity—the behavior of venules, arterioles, and especially capillaries—with emphasis on the close interdependence between structure and function, so as to enable the reader to deal more adequately with the accumulating mass of clinical and pathological information on the subject. An opening chapter outlines some general concepts. It is followed by chapters on the structure of the microcirculation, special and regional considerations, endothelium, functional behavior and local regulation, normal and abnormal vascular reactivity, capillary permeability, mechanisms of transcapillary exchange, vascular response to tissue injury, chemical mediators of tissue injury, experimental shock, and circulatory homeostasis.

Neither the text nor the 11 illustrations have the vividness of motion pictures now available. The reader is likely to be confused when the author writes "antedated" for "antiquated," "monitor" for "regulate," and "stigmata" for "stomata." The only mathematical expression in the book (page 84) is misprinted, so

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