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October 28, 1961

Changing Concepts of Common Bile Duct Anatomy and Physiology

Author Affiliations


From the departments of surgery, internal medicine, and research, The Denver Clinic, Presbyterian Hospital, and St. Joseph's Hospital.

JAMA. 1961;178(4):394-397. doi:10.1001/jama.1961.03040430030007

Preliminary evidence shows the possibility of intrinsic activity of the common bile duct and indicates that such activity may be separate from the physiologic activity of the sphincter of Oddi and the duodenal musculature. The suggestion is made that such activity could contribute to the symptomatology in biliary dyskinesia. The evidence comes from histologic studies of the common duct wall, a consideration of the anatomic relationships of the musculature of the sphincter of Oddi and the muscle fibers of the common bile duct wall, and from physiologic studies made through operative cinefluorographic cholangiography with simultaneous pressure tracings.