To the Editor:—
Since the original description by Thomson and Marson in 1953,1 there have been at least ten additional reports of the occurrence of polycythemia associated with uterine fibroids. All of these patients have had very large tumors; all have responded to hysterectomy with a prompt return of hematological values to normal. Various etiological factors have been postulated, including mechanical interference with pulmonary ventilation,2 ectopic erythropoiesis,3 renal vascular occlusion,4 hypoxia of bone marrow,5 and the occurrence of arteriovenous shunts within the tumor.6 The following is a report of an additional case. This patient had a large tumor also, and her hematological values returned to normal after a hysterectomy.
Report Of a Case:—
A 38-year-old white woman was admitted to the hospital on May 17, 1966, with complaints of dizziness, headaches, palpitation of the heart, and a ruddy discoloration of the skin. Symptoms had
Morton ED, Evans EF, Daines WP. Polycythemia and Uterine Myomata. JAMA. 1967;200(5):419. doi:10.1001/jama.1967.03120180107026