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May 29, 1967

Examination of the Blood in the Presence of Venous Thrombosis

Author Affiliations

From the departments of surgery and epidemiology and public health, Yale University School of Medicine, and the Yale—New Haven Medical Center, New Haven, Conn. Dr. Hume is now on sabbatical leave with the Department of Pharmacology, Royal College of Surgeons of England, London.

JAMA. 1967;200(9):747-750. doi:10.1001/jama.1967.03120220049007

Seven tests were compared in blood samples collected from normal individuals and patients with venous thrombosis. Three tests were found to have significance for discrimination: platelet entrapment in glass spheres, the hematocrit, and partial thromboplastin time of dilute plasma. A good, but incomplete, separation of individuals was effected by using a discriminant function based on these three variables.