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November 3, 1962

II. Histochemical Observations on Enzyme Distribution in Surgically Resected Human Myocardium

Author Affiliations

Albany, N.Y.

JAMA. 1962;182(5):534-537. doi:10.1001/jama.1962.03050440026008

The distribution of a group of enzymes was determined histochemically in the surgically resected auricular myocardium of 5 cases of rheumatic and 6 cases of congenital heart disease. The enzymes studied included succinic dehydrogenase, diphosphopyridine nucleotide diaphorase, adenosine triphosphatase (ATPase), glucose-6-phosphatase, alkaline and acid phosphatase, and nonspecific esterase. The only abnormality noted was the apparent marked reduction in ATPase activity in the myocardium.