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To the Editor:—
Had a large volume of reports been summarized, the editorial would have cited a figure of 40% for the incidence of hypothyroidism ten years after 131I therapy of hyperthyroidism rather than the extreme figure of 70%. More disturbing is the statement represented as fact: "Every major center uses repeated doses of 131I until remission is secured and this often requires doses in excess of 100 mc and four or more doses." A recent nationwide study of the results of various modes of therapy of hyperthyroidism, in which 23 major centers contributed data, lists 82% of the patients as having received one or two doses of 131I. This well-documented fact is difficult to reconcile with the statement that four or more doses of 131I are "often" necessary. Less than 6% of the patients received four or more doses of radioactive iodine and few, if
Workman JB. The Treatment of Hyperthyroidism. JAMA. 1967;201(5):331-332. doi:10.1001/jama.1967.03130050064029