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July 31, 1967

Chemotherapy of Disseminated Solid Tumors

Author Affiliations



by Fred J. Ansfield, 128 pp, 23 illus, $7.50, Springfield, Ill: Charles C Thomas, Publisher, 1946.

JAMA. 1967;201(5):335-336. doi:10.1001/jama.1967.03130050069042

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While this book attempts to "serve as a ready reference to the practicing physician," it misses its goal by a great deal. In order to do the job well, a book should be reliable, complete, and readable. This volume falls short in all these respects. The data quoted primarily concern the experience of one clinical group, using one drug, in a limited number of diseases. Hence there are no sections on lymphoma, and the treatment of genitourinary and gynecological malignancies is woefully brief. The data on fluorouracil do not emphasize that it can be given with effect by a number of routes and schedules, other than that used by the Wisconsin group. Problems of drug metabolism, as they relate to such important questions as whether toxicity is necessary for response, are not considered.

We find a lack of completeness or uniformity, from the table of contents through the lamentably small