August 7, 1967

Intelligence of Children Whose Mothers Have Biliary Tract Disease

Author Affiliations

From the Department of Research in Child Neurology (Dr. Churchill) and Laboratory of Psychobiology (Dr. Caldwell), Lafayette Clinic; departments of neurology (Dr. Churchill) and psychology (Dr. Caldwell), Wayne State University; and the Department of Obstetrics, Henry Ford Hospital (Dr. Ayers), Detroit. Dr. Churchill is presently affiliated with the National Institute of Neurological Diseases and Blindness, Bethesda, Md.

JAMA. 1967;201(6):482-484. doi:10.1001/jama.1967.03130060156022

The intelligence of children whose mothers had cholecystectomies for cholelithiasis, with or without cholecystitis, was compared to the intelligence of control children. Within the group with maternal biliary-tract disease a correlation between severity of maternal illness and IQ of the child was found. The speculation was proffered that the availability of linoleic acid for fetal brain development might be decreased in pregnant women who had biliary tract disease.