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August 28, 1967

Chronic Hypervitaminosis A in an Adult

Author Affiliations

From the Department of Medicine. St. Vincent's Hospital and Medical Center, New York. Dr. Di Benedetto is now at the US Naval Hospital, Beaufort, SC.

JAMA. 1967;201(9):700-702. doi:10.1001/jama.1967.03130090064022

Fatigue, musculoskeletal symptoms, skin changes, anorexia, weight loss, and hepatomegaly are the major manifestations of chronic hypervitaminosis A. Withdrawal of vitamin A results in complete recovery. This case is added to the 11 others previously documented in an attempt to stress the importance of earlier diagnosis and increased awareness.