Cerebral flow and metabolism were studied in a 44-year-old patient who was comatose due to St. Louis encephalitis. Although cerebral blood flow was normal, cerebral oxygen uptake was markedly reduced, and he had a significant reduction of arterial carbon dioxide tension.
Shapiro W, Eisenberg S. Cerebral Blood Flow and Metabolism in the Coma of St. Louis Encephalitis. JAMA. 1967;202(2):145-147. doi:10.1001/jama.1967.03130150113028