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October 9, 1967

Diagnosis and Treatment of Human Fascioliasis

Author Affiliations

From the Department of Medicine, Roosevelt Hospital, New York.

JAMA. 1967;202(2):149-151. doi:10.1001/jama.1967.03130150117030

Human Fasciola hepatica infection is a rare entity involving infestation of the liver and biliary tree with adult flukes, which can result in hepatitis, cirrhosis, and biliary tract inflammation, obstruction, and lithiasis. The patient had the typical diagnostic tetrad of fever, eosinophilic leukocytosis, tender hepatomegaly, and fluke ova in the stools. Treatment consists of emetine hydrochloride administration for hepatic involvement and common duct exploration for removal of flukes, with cholecystectomy for associated cholelithiasis. The combination of medical and surgical therapy can be expected to produce an arrest of this infection.